Compositions and methods for cancer therapy
OwnerHoun Simon Hsiainventor
Life of this patent
Estimating the term…
Abstract
Compositions and methods are described in which a nutritional supplement (such as a supplement that includes chromium and certain plant-derived materials and/or a supplement that includes a selenium yeast peptide complex and fish oil is used to provide an immunotherapeutic effect, which can be demonstrated by modulation of cell-surface markers targeted by conventional immunotherapeutic drugs. The nutritional supplements can be used in combination with other antineoplastic therapies, such as radiation and/or chemotherapeutic agents. Such combination therapy can provide a synergistic effect in regard to modulation of cell surface markers that serve as immunotherapy targets.
Claims20
1-52. (canceled)
A method providing immunotherapy to an individual with cancer, comprising administering a nutritional supplement comprising selenium and fish oil in an amount sufficient to modify expression of a biological marker associated with an anti-neoplastic immune function.
A method of activating immune cells to enhance anti-tumor activity, comprising:
- isolating an immune cell from an individual to be treated for cancer;
- contacting the isolated immune cell with an activating formulation comprising selenium and fish oil in an amount effective to modulate expression of a protein associated with immune cell activation to generate an activated immune cell;
- and
- administering the activated immune cell to the individual.
A method of modulating expression of an immune checkpoint or immunotherapy-associated protein in a cell, comprising administering a supplement comprising selenium and fish oil.
Dependencies are inferred from the claim text.