Inhibition of Monoamine Oxidase Subtype A (MAOA) Mitigates Cardiovascular Calcification
AssigneeThe Brigham and Women's Hospital, Inc.
InventorsJulius Decano, Elena Aikawa, Masanori Aikawa, Yukio Francisco Iwamoto
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Abstract
Compositions and methods for use in the treatment of disorders associated with aortic valve calcification. In some embodiments, the disorder is calcific aortic stenosis (CAS). Generally, the methods include administering a therapeutically effective amount of an inhibitor of MAOA as described herein, to a subject who is in need of, or who has been determined to be in need of, such treatment.
Claims12
A method for the treatment of a disorder associated with aortic valve calcification, the method comprising administering a therapeutically effective amount of an inhibitor of monoamine oxidase subtype A (MAOA), to a subject who is in need of, or who has been determined to be in need of, such treatment.
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Dependencies are inferred from the claim text.