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US 2022/0175760 A1Published application
Pharmaceutical formulations
AssigneeJanssen Pharmaceutica NV
InventorsKristof Leonard KIMPE, Sanket Manoj SHAH, Audrey Antoinette Renee LATHUILE, Rene HOLM, Thomas Eddy R NEEFS, Hana PROKOPCOVA
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Abstract
The invention relates to pharmaceutical formulations comprising an active pharmaceutical ingredient, a polyethylene glycol having a freezing point of at least about 30° C., and a crystallisation rate inhibitor. Solid dosage forms comprising said pharmaceutical formulations, processes for preparing these and their use in methods of treatment are also described.
Claims39
A pharmaceutical formulation, comprising:
- a) a polyethylene glycol having a freezing point of at least about 30° C.;
- b) an active pharmaceutical ingredient that is soluble in molten polyethylene glycol wherein the polyethylene glycol is as defined in a);
- and
- c) a crystallisation rate inhibitor.
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30-31. (canceled)
A solid dosage form comprising
- a) a polyethylene glycol having a freezing point of at least about 30° C.;
- and
- b) an active pharmaceutical ingredient that is soluble in molten polyethylene glycol wherein the polyethylene glycol is as defined in a);
- wherein the solid dosage form is a HPMC capsule.
1 more element
Dependencies are inferred from the claim text.