Methods and compositions for oral pilocarpine liquid
AssigneeROMEG Therapeutics LLC
InventorsIndu MUNI, Naomi VISHNUPAD
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Abstract
Liquid oral pilocarpine formulations are described herein. Methods of using the liquid oral pilocarpine formulations are also provided.
Claims29
A method of treating a pilocarpine sensitive disorder, comprising orally administering a composition for ingestion, comprising a liquid pilocarpine formulation to a subject having a pilocarpine sensitive disorder in an effective amount to treat the disorder.
A pharmaceutical solution or suspension suitable for oral administration comprising pilocarpine and a pharmaceutically acceptable solvent system comprised of one or more agents selected from the group consisting of water, glycols, buffering agents, sweeteners, flavoring agents, preservatives and dyes.
A pharmaceutical solution or suspension suitable for oral administration comprising:
- Ingredient
- mg/ml
- Pilocarpine HCl
- 1.000
- Hydroxyethylcellulose (Natrasol 250 HHX)
- 2.000
- Citric Acid, Anhydrous, USP
- 5.000
- FD&C Red No. 40
- 0.015
- FD&C Blue No. 1
- 0.005
- Flavor Grape 59266/A
- 0.400
- Glycerin, USP
- 200.000
- Propylene Glycol, USP
- 50.000
- Poloxamer 407
- 5.000
- Simethicone Emulsion
- 0.500
- Sodium Citrate, Dihydrate
- 3.500
- Sodium Benzoate, NF
- 1.500
- Sucralose, NF
- 0.150
- Purified Water, USP
- QS
Dependencies are inferred from the claim text.