Phenprocoumon tts
OwnerDirk TRENZ, Thomas HILLEinventors
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Abstract
The present invention relates to a transdermal therapeutic system for the cutaneous administration of phenprocoumon, comprising an active-substance-impermeable backing layer, an adhesive matrix layer and optionally a removable protective layer, the adhesive matrix layer containing phenprocoumon and at least one matrix polymer, and the content of phenprocoumon in the matrix polymer being ≤7.5 wt. %. By virtue of the low load, it is ensured that the system releases the active ingredient substantially in high release rates, because high thermodynamic activity of the active ingredient is achieved. The present invention also relates to a method for producing a corresponding transdermal therapeutic system.
Claims20
A transdermal therapeutic system for the cutaneous administration of phenprocoumon, comprising an active-substance-impermeable backing layer, an adhesive matrix layer and optionally a removable protective layer, characterised in that the adhesive matrix layer contains phenprocoumon with a content ≤12% by weight and at least one matrix polymer.
2-15. (canceled)
A transdermal therapeutic system for the cutaneous administration of phenprocoumon, comprising an active-substance-impermeable backing layer, an adhesive matrix layer and optionally a removable protective layer, characterised in that the adhesive matrix layer contains phenprocoumon with a content of 0.5 to ≤12% by weight and at least one matrix polymer, and in that the matrix polymer consists of neutral polymers.
Dependencies are inferred from the claim text.