Oils with anti-inflammatory activity containing natural specialized proresolving mediators and their precursors
AssigneeSolutex NA LLC
InventorsGerhardus Lucas Bannenberg, Charles Nicholas Serhan, Fernando Moreno Egea
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Abstract
The present invention encompasses oils that have anti-inflammatory or resolution-stimulating activity that contain or are enriched with Specialized Proresolving Mediators (SPM) or SPM precursors, which originate from an oil obtained from organisms containing long chain omega-3 polyunsaturated fatty acids, such as fish, crustaceae, algae, and mollusks. The invention also encompasses a method for the production of these oils, and the utilization of the oils for nutritional supplements, pharmaceutical formulations, and cosmetic formulations, which can be employed for treating an inflammatory condition.
Claims19
A composition, comprising:
- a plurality of triglycerides each having a glycerol backbone and three fatty acids chemically bound thereto, wherein:
- a triglyceride of the plurality of triglycerides has 18-HEPE fatty acid chemically bound thereto,
- a triglyceride of the plurality of triglycerides has 17-HDHA fatty acid chemically bound thereto,
- a triglyceride of the plurality of triglycerides has 15-HEPE fatty acid chemically bound thereto,
- a triglyceride of the plurality of triglycerides has 12-HEPE fatty acid chemically bound thereto,
- a triglyceride of the plurality of triglycerides has 11-HEPE fatty acid chemically bound thereto,
- each of the plurality of triglycerides has as a fatty acid chemically bound thereto docosahexaenoic acid (DHA) or eicosapentaenoic acid (EPA),
- 17-HDHA is present in an amount of at least about 100 mg/L, and
- the composition is encapsulated in a capsule shell.
Dependencies are inferred from the claim text.