Promotion of lymphatic function
AssigneesUniversitaet Basel, Eth Zuerich
InventorsMichael Detmar, Matthias Hamburger, Olivier Potterat, Adriana Sliwa-Primorac
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Abstract
The present invention refers to lipophilic extracts of members of the Iridaceae family, such as Iris germanica and/or Iris pallida, that have been found to promote lymphatic function. These extracts are suitable for the treatment of skin inflammation, rheumatoid arthritis, impaired wound healing, chronic inflammatory diseases, chronic airway inflammation, inflammatory bowel disease, rosacea, primary and/or secondary lymphedemas. The most active components were found to be the iridals.
Claims9
A method for treating a disease related to impaired lymphatic function comprising administering to a subject in need thereof a lipophilic extract of a member of the Iridaceae family selected from the group consisting of Iris germanica, Iris pallida, and mixtures thereof, wherein the disease is selected from the group consisting of primary lymphedemas, and secondary lymphedemas.
A method for treating a disease related to impaired lymphatic function comprising administering to a subject in need thereof one or more iridals, wherein said disease is selected from group consisting of primary lymphedemas, and secondary lymphedemas.
A method for treating under-eye puffiness, swollen legs, and cellulite comprising administering to a subject in need thereof the cosmetic or pharmaceutical composition comprising a lipophilic extract of a member of the Iridaceae family selected from the group consisting of Iris germanica, Iris pallida, and mixtures thereof.
A method for preparing a lipophilic extract of at least one member of the Iridaceae family, wherein at least a part of the rhizome is extracted with carbon dioxide (CO2) comprising 5 to 10% ethanol.
Dependencies are inferred from the claim text.