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US 2022/0175690 A1Published application
Novel drug delivery composition and process for blood-brain barrier crossing
AssigneePhosphorex, Inc.
InventorsBin Wu, Nicholas Boylan, Zimeng Wang, Jieni Xu
Life of this patent
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Abstract
This invention provides polymeric nanoparticles presenting non-conjugated BBB-crossing ligands on their surfaces, compositions and methods of use thereof, as well as non-conjugation methods to produce nanoparticles having BBB-crossing agents on their surfaces.
Claims14
A method of delivering an active agent to a central nervous system in a mammal comprising administering particles encapsulating the active agent comprising a biodegradable polymer and a surfactant intertwined on the surface thereof.
Dependencies are inferred from the claim text.