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US 2022/0175675 A1Published application
Encapsulating molecules in fat globules
AssigneeThe Regents of the University of California
InventorsNitin NITIN, Maha ALSHEHAB
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Abstract
Provided herein are methods of encapsulating molecules in milk fat globules and oleosomes, and compositions and pharmaceutical formulations of compositions with molecules encapsulated in milk fat globules and oleosomes.
Claims78
A method for encapsulating at least one compound, comprising providing the at least one compound;
- mixing a plurality of milk fat globules or oleosomes with the at least one compound to obtain a mix;
- incubating the mix to allow the at least one compound to diffuse into at least one substructure of a fraction of the plurality of the milk fat globules or oleosomes comprising the at least one compound.
A composition comprising:
- a plurality of milk fat globules or oleosomes;
- at least one compound;
- an amount of a pharmaceutically acceptable solvent or food-grade solvent;
- wherein the at least one compound is encapsulated within a fraction of the plurality of milk fat globules or oleosomes.
1 more element
A composition comprising:
- a plurality of milk fat globules or oleosomes;
- at least one compound;
- an amount of a pharmaceutically acceptable solvent or food-grade solvent;
- wherein the at least one compound is encapsulated within a fraction of the plurality of milk fat globules or oleosomes, and
- wherein the composition is configured to deliver the compound at a site of interest.
2 more elements
A composition comprising:
- at least one compound encapsulated within a fraction of the plurality of milk fat globules or oleosomes by a method, comprising
- providing a plurality of milk fat globules or oleosomes;
- providing at least one compound;
- mixing the plurality of milk fat globules or oleosomes with the at least one compound to obtain a mix;
- incubating the mix to allow the at least one compound to diffuse into at least one substructure of a fraction of the plurality of milk fat globules or oleosomes comprising the at least one compound,
- thereby encapsulating the at least one compound;
- wherein the composition is configured to deliver the compound at a site of interest.
4 more elements
A composition comprising:
- an intact milk fat globule or oleosome;
- at least one compound;
- wherein the at least one compound is encapsulated within the intact milk fat globule.
Dependencies are inferred from the claim text.