Back to results
US 2022/0175669 A1Published application
Chewable pharmaceutical product for delivery of colesevelam hydrochloride
AssigneeCosette Pharmaceuticals, Inc.
InventorTommy L. CHAU
Life of this patent
Estimating the term…
Abstract
A chewable pharmaceutical product comprises a matrix comprising: a binder, a bulking agent, a lubricant, a humectant, an emulsifier, and optionally a flavoring, wherein the binder comprises one or more maltitol syrups, which are present in the pharmaceutical product in an amount in the range of 60-70% by weight; and colesevelam hydrochloride.
Claims5
A method of making a chewable pharmaceutical product for delivery of colesevelam hydrochloride comprising:
- (ix) heating an amount of one or more maltitol syrups to a temperature of in the range of 120-160° F.;
- (x) melting a lubricant;
- (xi) blending dry ingredients in a mixer, the dry ingredients comprising:
- at least colesevelam hydrochloride and a bulking agent,
- (xii) adding the one or more maltitol syrups, the lubricant, a humectant, and an emulsifier to the dry ingredients in the mixer;
- (xiii) optionally adding one or more of a flavoring, coloring, and an antioxidant to the mixture;
- (xiv) mixing all of the ingredients until substantially uniform to form an active-ingredient-containing matrix;
- (xv) extruding the active-ingredient-containing matrix and then cutting to form the chewable pharmaceutical product,
- wherein the amount of the one or more maltitol syrups in the chewable pharmaceutical product is in the range of 60-70% by weight;
- (xvi) packaging the chewable pharmaceutical product.
7 more elements
Dependencies are inferred from the claim text.