Injection formulation composition containing mesenchymal stem cell-hydrogel and method for preparing, freezing and defrosting same
AssigneeAnterogen Co., Ltd.
InventorsSung-Koo LEE, Mi-Hyung KIM
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AssigneeAnterogen Co., Ltd.
InventorsSung-Koo LEE, Mi-Hyung KIM
Estimating the term…
The present invention relates to a composition containing injectable mesenchymal stem cell-hydrogel and a method of preparing the same. Specifically, in a mesenchymal stem cell-hydrogel composition for injection prepared by a method of the present invention, since stem cells are attached to scaffolds in hydrogel beads, the stem cells are not easily lost or killed after the injection, and thus there is an advantage that an engraftment rate increases since the paracrine effect of the stem cells is continuously exhibited, and the stem cells are gradually released as hydrogel is degraded. In addition, the present invention has an advantage that healthy cells can be used without damages in cell membranes since injection formulation can be prepared without a treatment with proteolytic enzymes, and also a cryopreservation solution is easily removed from the mesenchymal stem cell-hydrogel beads even after freezing and thawing.
A cell-hydrogel composition comprising:
A method of preparing a cell-hydrogel composition, the method comprising:
A method of preventing or improving a musculoskeletal disease, a fistula disease, or an inflammatory disease, the method comprising:
A method of treating a musculoskeletal disease, a fistula disease, or an inflammatory disease, the method comprising:
(canceled)
Dependencies are inferred from the claim text.