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US 2022/0175634 A1Published application
Peptide nanoparticles and uses therefor
AssigneeAnterios, Inc.
InventorsJonathan Edelson, Timothy Kotyla
Life of this patent
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Abstract
The present invention provides nanoparticle compositions including one or more peptides. The present invention achieves transdermal delivery of such peptides without the need for peptide modification, or for use of chemical or mechanical abrasion or disruption of skin.
Claims17
A nanoparticle composition in an aqueous media comprising:
- a surfactant,
- a hydrophilic component comprising at least one polysaccharide selected from the group consisting of sucrose and trehalose,
- an unmodified peptide less than 40 amino acids in length, and
- a biologically active agent comprising a serotype A botulinum toxin or botulinum toxin complex,
- wherein the nanoparticle composition self-assembles into micelles, and
- wherein the nanoparticle composition is free of albumin.
3 more elements
A nanoparticle composition in an aqueous media comprising:
- a surfactant comprising a polysorbate,
- a hydrophilic component comprising at least one polysaccharide selected from the group consisting of sucrose and trehalose,
- an unmodified peptide less than 40 amino acids in length, and
- a biologically active agent comprising a serotype A botulinum toxin or botulinum toxin complex,
- wherein the nanoparticle composition self-assembles into micelles, and
- wherein the nanoparticle composition is free of albumin.
3 more elements
Dependencies are inferred from the claim text.