Uses of novel fatty acid desaturases and elongases and products thereof
AssigneeBASF Plant Science GmbH
InventorsJörg Bauer, Johnathan A. Napier, Olga Sayanova
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Abstract
The invention provides isolated nucleic acid molecules which encode novel fatty acid desaturases and elongases from the organism Emiliana huxleyi. The invention also provides recombinant expression vectors containing desaturase or elongase nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g. arachidonic acid (ARA), eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA).
Claims15
A polynucleotide comprising a nucleic acid sequence elected from the group consisting of:
- a) a nucleic acid sequence having a nucleotide sequence as shown in SEQ ID NOs:
- 1, 3, 5, 7 or 9;
- b) a nucleic acid sequence encoding a polypeptide having an amino acid sequence as shown in SEQ ID NOs:
- 2, 4, 6, 8 or 10;
- c) a nucleic acid sequence being at least 70% identical to the nucleic acid sequence of a) or b), wherein said nucleic acid sequence encodes a polypeptide having desaturase or elongase activity;
- d) a nucleic acid sequence encoding a polypeptide having desaturase or elongase activity and having an amino acid sequence which is at least 82% identical to the amino acid sequence of any one of a) to c);
- and
- e) a nucleic acid sequence which is capable of hybridizing under stringent conditions to any one of a) to d), wherein said nucleic acid sequence encodes a polypeptide having desaturase or elongase activity.
Dependencies are inferred from the claim text.