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US 2022/0168726 A1Published application
Pipette tip containing one or more barriers
OwnerSergey Smulevitchinventor
Life of this patent
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Abstract
A pipette tip according to certain embodiments includes a proximal end, a distal end, and a reagent chamber. The proximal end is dimensioned to fit on an end of a pipettor, and includes a proximal end opening. The distal end includes a distal end opening. The reagent chamber has a reagent composition disposed therein. The reagent chamber is defined at least in part by a proximal barrier and a distal barrier. The reagent composition is operable to pass through the distal end opening upon rupturing of the distal barrier.
Claims20
A pipette tip comprising:
- a proximal end dimensioned to fit on an end of a pipettor, the proximal end including a proximal end opening;
- a distal end including a distal end opening;
- and
- a reagent chamber having a reagent composition disposed therein, wherein the reagent chamber is defined at least in part by a proximal barrier and a distal barrier;
- wherein the reagent composition is operable to pass through the distal end opening upon rupturing of the distal barrier.
2 more elements
(canceled)
(canceled)
A method, comprising:
- attaching a proximal end of a pipette tip to a pipettor, wherein the pipette tip comprises a reagent composition and a barrier retaining the reagent composition within the pipette tip;
- and
- rupturing the barrier, thereby causing the reagent composition to pass through a distal end of the pipette tip and into a vessel;
- wherein rupturing the barrier comprises actuating the pipettor;
- and
- wherein actuating the pipettor results in formation of a pressure differential that ruptures the barrier.
3 more elements
A method, comprising:
- attaching a proximal end of a pipette tip to a pipettor, wherein the pipette tip comprises a reagent composition and a barrier retaining the reagent composition within the pipette tip;
- and
- rupturing the barrier, thereby causing the reagent composition to pass through a distal end of the pipette tip and into a vessel;
- wherein rupturing the barrier comprises actuating the pipettor;
- and
- wherein the pipette tip further comprises a movable lance, and wherein actuating the pipettor causes movement of the lance such that the lance pierces the barrier.
3 more elements
A method, comprising:
- attaching a proximal end of a pipette tip to a pipettor, wherein the pipette tip comprises a reagent composition and a barrier retaining the reagent composition within the pipette tip;
- and
- rupturing the barrier, thereby causing the reagent composition to pass through a distal end of the pipette tip and into a vessel;
- wherein the vessel comprises a lance, and wherein rupturing the barrier comprises inserting the lance via the distal end of the pipette tip such that the lance pierces the barrier.
1 more element
Dependencies are inferred from the claim text.