Nanoparticles comprising copolymeric or homopolymeric compounds which comprise cyanoacrylate subunits
AssigneeSintef Tto AS
InventorsRuth Schmid, Peter Molesworth, Yrr Mørch
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Abstract
The invention relates to a nanoparticle comprising copolymeric or homopolymeric compounds which comprise cyanoacrylate subunits according to formula 2A, wherein each R1 is independently selected from the group consisting of 2-ethylhexyl, 2-phenylethyl, neopentyl, 1-pentyl, 2-pentyl, 3-pentyl, 3,3-dimethyl-1-butyl, 3-methylbutyl, -heptyl, 2-heptyl, and 3-heptyl; and wherein the nanoparticle further comprises an active agent. The invention also provides compositions comprising the nanoparticles, and the nanoparticles for use in therapy or diagnosis, such as in the treatment of cancer or an infection, or for use in diagnostic imaging.
Claims28
A nanoparticle comprising copolymeric or homopolymeric compounds which comprise cyanoacrylate subunits according to formula 2A:
- wherein each R1 is independently selected from the group consisting of 2-ethylhexyl, 2-phenyl-ethyl, neopentyl, 1-pentyl, 2-pentyl, 3-pentyl, 3,3-dimethyl-1-butyl, 3-methylbutyl, 1-heptyl, 2-heptyl, and 3-heptyl;
- and wherein the nanoparticle further comprises an active agent.
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Dependencies are inferred from the claim text.