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OwnerSimon Robert HALL, Jason Leigh POTTICARY +1inventors
InventorsSimon Robert HALL, Jason Leigh POTTICARY, Charlie Lewis HALL
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A solidification or crystallization method is disclosed, which includes providing at least a first organic compound and at least one volatile co-former organic compound. A mixture of at least the first organic compound and the co-former organic compound is formed, wherein either the first organic compound or the volatile co-former organic compound includes a hydrogen acceptor moiety and the other includes a hydrogen donor moiety, thereby allowing the formation of hydrogen bonds between the first organic compound and the volatile co-former organic compound. The mixture is allowed to stand for sufficient time for the mixture to liquify at a temperature below that of the melting points of the components, thereby forming a liquid mixture. The volatile co-former organic compound is allowed to evaporate, thereby resulting in crystallization of at least the first organic compound. The method can be a co-crystallization method if there are two organic compounds.
1-23. (canceled)
A solidification or crystallization method, the method comprising:
A eutectic mixture comprising phenol and a first organic compound selected either from the group consisting of carbamazepine, paracetamol, metacetamol, ibuprofen, tadalafil, metaxalone, benzamide, 2-methoxybenzamide, 2-ethoxybenzamide, indomethacin, lamotrigine, and harmine, or from a mixture of two or more of carbamazepine, paracetamol, metacetamol, ibuprofen, tadalafil, metaxalone, benzamide, 2-methoxybenzamide, 2-ethoxybenzamide, indomethacin, lamotrigine, and harmine.
A co-crystalline solid comprising metaxalone and a second component comprising at least one of benzamide or carbamazepine;
Dependencies are inferred from the claim text.