System for Monitoring and Controlling the Composition of Charged Droplets for Optimum Ion Emission
OwnerThomas R. Covey, Chang Liu +1inventors
InventorsThomas R. Covey, Chang Liu, Stephen A Tate
Life of this patent
Estimating the term…
Loading patent…
OwnerThomas R. Covey, Chang Liu +1inventors
InventorsThomas R. Covey, Chang Liu, Stephen A Tate
Estimating the term…
A device that produces charged droplets whose composition is optimized for the creation of ions by electro spray composed of: a transport device that is operative to transfer sample components from a liquid sample to a processing chamber, a flowing stream of liquid through the processing chamber into which the samples are deposited, a controller mechanism operative to control the amount of sample transferred, a transport tube through which the flowing liquid containing the sample is directed to an electro spray emitter with a high electric field at the exit, a flow of expanding gas surrounding the electro spray emitter creating a pressure drop at the exit, and, a mass spectrometer for measuring the number of ions produced from the charged droplets emanating from the emitter; wherein the dilution of the sample in the processing chamber and transport fluid is from 100 to 10,000-fold.
A device that produces charged droplets whose composition is optimized for the creation of ions by electrospray comprises of:
A method for adjusting a composition of the charged droplets that create gas phase ions to compensate for samples whose composition is outside the boundaries of those required for optimal ion production by:
(canceled)
(canceled)
Dependencies are inferred from the claim text.