Therapeutic agent for corneal diseases
AssigneeNissan Chemical Corporation
InventorsNatsuki FUKASAWA, Taito NISHINO, Rina WATANABE
Life of this patent
Estimating the term…
Abstract
The present invention relates to a novel means for treating corneal diseases. The present invention provides a therapeutic agent for corneal diseases, containing a compound represented by the following formula (I): wherein each symbol is as defined in the DESCRIPTION, or a salt thereof.
Claims30
-9. (canceled)
A method for treating a corneal disease, comprising administering a compound represented by the following formula (I) or a salt thereof to a subject in need thereof:
- {wherein, X is —NHCO—, R1 is —Y—NH—Z—Ar (wherein Y and Z are each independently a single bond, or an alkylene group having 1-6 carbon atoms and optionally having substituent(s), and Ar is an aryl group optionally having substituent(s)), R2 is an alkyl group having 1-6 carbon atoms and optionally having substituent(s), R3 is a hydroxy group, and n is 0, 1, or 2}.
A method for promoting the proliferation of a corneal epithelial cell or a corneal endothelial cell, comprising culturing the corneal epithelial cell or the corneal endothelial cell in a medium composition comprising a compound represented by the following formula (I) or a salt thereof:
- {wherein, X is —NHCO—, R1 is —Y—NH—Z—Ar (wherein Y and Z are each independently a single bond, or an alkylene group having 1-6 carbon atoms and optionally having substituent(s), and Ar is an aryl group optionally having substituent(s)), R2 is an alkyl group having 1-6 carbon atoms and optionally having substituent(s), R3 is a hydroxy group, and n is 0, 1, or 2}.
A compound represented by the following formula:
- or a salt thereof.
Dependencies are inferred from the claim text.