Peptide synthesis instrumentation

A chemical synthesis device comprising:

• a reaction vessel;
• a lower connector configured to provide sealed engagement to a lower tapered fitting of a reaction vessel;
• an upper connector configured to provide sealed engagement to an upper tapered fitting of the reaction vessel;
• a knob attached to the upper connector;
• and
• an upper connector path formed in a housing of the chemical synthesis device, the upper connector path permitting movement of the knob and upper connector upward to disconnect the upper connector from the upper tapered fitting, and downward to a reaction vessel connection position where the upper connector engages with the upper tapered fitting of the reaction vessel.

A double reaction vessel system for a chemical synthesis device, comprising:

• a first reaction chamber having fittings at an upper end and a lower end thereof;
• a second chamber fluidly connected at its lower end to the upper end of the first reaction chamber;
• a waste connection at an upper end of the second chamber;
• a first inert gas connection at the upper end of the second chamber, the first inert gas connection operable to provide an inert gas flow through the second chamber, from the upper end to the lower end, and into the first reaction chamber;
• and
• a second inert gas connection operable to provide an inert gas into the first reaction chamber via the lower end thereof.