Computer-assisted method for determining a microfluidic circuit architecture reproducing a neuronal circuit

A computer-assisted method for determining a microfluidic circuit, the microfluidic circuit being configured to reproduce a neuronal circuit, and comprising the following steps:

• obtaining a description of the neuronal circuit, the description of the neuronal circuit comprising a plurality of neuronal populations and at least one neuronal connection, each neuronal population comprising at least one neuron, each neuronal connection of the at least one neuronal connection linking one neuronal population of the plurality of neuronal populations to another neuronal population of the plurality of neuronal populations by a neuronal link between the at least one neuron of the neuronal population and at least one other neuron of the other neuronal population;
• determining at least one first parameter for each node of a plurality of nodes of the microfluidic circuit, each node of the plurality of nodes of the microfluidic circuit being associated with and configured to receive one neuronal population among the plurality of neuronal populations of the neuronal circuit;
• determining at least one second parameter for at least one connection of the microfluidic circuit, each connection of the at least one connection linking one node of the plurality of nodes to at least one other node of the plurality of nodes, each connection of the at least one connection of the microfluidic circuit being associated with and configured to receive one neuronal connection of the at least one neuronal connection of the neuronal circuit;
• determining the positioning of each node of the plurality of nodes and of each connection of the at least one connection.