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US 2022/0119783 A1Published application
Recombinant host cells for the production of malonate
AssigneeLygos, Inc.
InventorsJeffrey A. Dietrich, Jeffrey L. Fortman, Eric J. Steen
Life of this patent
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Abstract
Systems and methods for the production of malonate in recombinant host cells.
Claims12
-15. (canceled)
A malonyl-CoA hydrolase having at least 75% identity with SEQ ID NO:
- 9.
A recombinant Pichia kudriavzevii host cell that comprises one or both of:
- a heterologous Pseudomonas fulva malonyl-CoA hydrolase having at least 75% identity with SEQ ID NO:
- 9, and
- a heterologous Saccharomyces cerevisiae (Sc) aldehyde dehydrogenase (ALD) selected from Sc ALD 2 to 6.
26-42. (canceled)
Dependencies are inferred from the claim text.