Salt of egfr inhibitor, crystal form, and preparation method therefor
AssigneeChia Tai Tianqing Pharmaceutical Group Co., Ltd.
InventorsLingyun WU, Xile LIU, Charles Z. DING, Shuhui CHEN, Lihong HU, Lele ZHAO, Wei PAN, Guoping HU, Jian LI, Ning ZHAO, Jun ZHAO
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Abstract
Provided are a salt of an EGFR inhibitor, a crystal form thereof and a preparation method therefor, and an application of the salt and the crystal form in the preparation of a treatment for non-small cell lung cancer. The salt has a structure as shown in formula (II).
Claims22
A compound of formula (II),
- wherein x is selected from 3.0-5.0.
The compound of formula (II) according to claim 19, wherein the X-ray powder diffraction pattern of the crystalline form is shown in FIG. 13.
(canceled)
The compound of formula (II) according to claim 20, wherein the X-ray powder diffraction pattern of the crystalline form is shown in FIG. 4.
(canceled)
The compound of formula (II) according to claim 21, wherein the X-ray powder diffraction pattern of the crystalline form is shown in FIG. 7.
(canceled)
The compound of formula (II) according to claim 22, wherein the X-ray powder diffraction pattern of the crystalline form is shown in FIG. 10.
14-16. (canceled)
Dependencies are inferred from the claim text.