Biodegradable chitosan microneedle patch for transdermal delivery for livestock pain management
OwnerJorge L. Almodovar, Lauren Greenlee +2inventors
InventorsJorge L. Almodovar, Lauren Greenlee, Jeremy G. Powell, David Alfonso Castilla-Casadiego
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Abstract
Disclosed herein is a microneedle array comprising a substrate and a plurality of microneedles extending therefrom, wherein the microneedles comprise a biodegradable polymer and an effective amount of an analgesic or an anti-inflammatory therapeutic agent. Methods of using and making the microneedle array are also disclosed.
Claims20
A microneedle array comprising a substrate and a plurality of microneedles extending therefrom, wherein the microneedles comprise a biodegradable polymer and an effective amount of an analgesic or an anti-inflammatory therapeutic agent and wherein the microneedles have a height configured to pierce the stratum corneum.
A method for preparing a microneedle array, the method comprising:
- applying a microneedle composition, the microneedle composition comprising a biodegradable polymer and an effective amount of an analgesic or an anti-inflammatory therapeutic agent to a mold, wherein the mold comprises a plurality recesses configured to prepare a plurality of microneedles;
- distributing the microneedle composition within the plurality of recesses;
- setting the microneedle array;
- and
- releasing the microneedle array from the mold.
Dependencies are inferred from the claim text.