Apparatuses for optical and mass spectrometry detection
AssigneeGMJ Technologies, Inc.
InventorOluwatosin O. Dada
Life of this patent
Estimating the term…
Abstract
Presented herein are apparatuses for use in capillary separations. An apparatus includes a coupling that integrates a capillary with a voltage source, a sheath liquid system, a fluid exit port, and a manifold. The coupling may be an elbow connector or equivalent. The manifold receives incident light from an incident light input, and emitted light is collected by a collected light output. The capillary enters the manifold at an input for the capillary, traverses the coupling, and terminates at the fluid exit port, for example an electrospray emitter. The capillary may also enter the manifold at an input for the capillary and terminates inside the manifold.
Claims21
1-20. (canceled)
A cartridge comprising:
- a capillary;
- a coupling integrating the capillary with a voltage source, a fluid exit port, and a unitary optical manifold;
- and
- the unitary optical manifold comprising an incident light input, at least one collected light output, and an input for the capillary;
- wherein the capillary enters the input for the capillary and terminates at the fluid exit port;
- wherein the incident light input is at least one input window in the unitary optical manifold and the at least one collected light output is at least one output window in the unitary optical manifold;
- and
- wherein the incident light is injected into the capillary at the at least one input window in the unitary optical manifold and the capillary transmits light to collection optics via the at least one output window in the unitary optical manifold.
A cartridge comprising:
- a microfluidic channel;
- a unitary optical manifold comprising an incident light input, at least one collected light output, and the microfluidic channel linearly traversing the optical manifold from an input for the microfluidic channel to at least one of a spray emitter and a waste receptacle;
- wherein the incident light input is at least one input window in the unitary optical manifold and the at least one collected light output is at least one output window in the unitary optical manifold;
- and
- collection optics adjacent to the at least one output window in the unitary optical manifold, the collection optics comprising at least one micro GRIN lens.
A system comprising:
- a cartridge comprising:
- at least one of a capillary and a microfluidic channel;
- a coupling integrating the at least one of the capillary and the microfluidic channel and a unitary optical manifold and a fluid exit port;
- and
- the unitary optical manifold comprising an incident light input, at least one collected light output, and an input for the at least one of the capillary and the microfluidic channel;
- wherein the at least one of the capillary and the microfluidic channel enters the input for the at least one of the capillary and the microfluidic channel and terminates at the fluid exit port;
- wherein the incident light input is at least one input window in the unitary optical manifold and the at least one collected light output is at least one output window in the unitary optical manifold;
- and
- wherein the incident light is injected into the at least one of the capillary and the microfluidic channel at the at least one input window in the unitary optical manifold and the at least one of the capillary and the microfluidic channel transmits light to collection optics via the at least one output window in the unitary optical manifold;
- at least one collection optics adjacent to the at least one collected light output in the unitary optical manifold, the at least one collection optics comprising at least one micro GRIN lens;
- at least one incident light source;
- and
- at least one detector.
Dependencies are inferred from the claim text.