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US 2022/0101967 A1Published application
Methods for automatic cohort selection in epidemiologic studies and clinical trials
AssigneeEngooden Health Inc.
InventorsNeel Master, Peeyush Kumar
Life of this patent
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Abstract
Generally, the method provides an interface for clinical research organizations to estimate, in real-time, an eligible patient population for a clinical study, as well as a point-of-care interface that can alert patients of their eligibility in a clinical study. Thus, the method provides improved identification of clinical cohorts and can quickly match patients with clinical studies that fit their medical needs.
Claims1
A method for selecting a cohort for a clinical study, comprises:
- accessing from an electronic health record database, an unstructured electronic health record for each patient in a population of patients;
- for each patient in the population of patients:
- transforming the associated unstructured electronic health records of the patient into a patient graph, the patient graph representing a set of clinical concepts and corresponding semantic roles for the patient;
- and
- appending the patient graph to a set of patient graphs;
- at a clinical research interface, recording a first set of inclusion and exclusion criteria;
- transforming the first set of inclusion and exclusion criteria into a first target graph representing a first set of target clinical concepts for a clinical trial;
- for each patient in the population of patients, in response to alignment between the patent graph of the patient and the first target graph, appending the patient to a first subpopulation of patients;
- rendering a first representation of the first subpopulation of patients within the clinical research interface;
- at the clinical research interface, recording a second set of inclusion and exclusion criteria;
- transforming the first set of inclusion and exclusion criteria and the second set of inclusion and exclusion criteria into a second target graph for the clinical trial;
- and
- for each patient in the population of patients, in response to alignment between the patient graph of the patient and the second target graph, appending the patient to a second subpopulation of patients;
- rendering a second representation of the second subpopulation of patients within the clinical research interface;
- recording a selection of a potential clinical cohort from the second subpopulation of patients;
- and
- in response to access of a particular electronic health record of a particular patient included in the potential clinical cohort at a point-of-care interface, rendering an indication of the particular patient's eligibility for the clinical trial.
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