Loading patent…
AssigneeScipher Medicine Corporation
InventorsSusan GHIASSIAN, Theodore R. MELLORS, Marc SANTOLINI, Asher AMELI, Nancy SCHOENBRUNNER, Viatcheslav R. AKMAEV, Keith J. JOHNSON
Estimating the term…
Presented herein are systems and methods for developing classifiers useful for predicting response to particular treatments. For example, in some embodiments, the present disclosure provides a method of treating subjects suffering from an autoimmune disorder, the method comprising a step of: administering an anti-TNF therapy to subjects who have been determined to be responsive via a classifier established to distinguish between responsive and non-responsive prior subjects in a cohort who have received the anti-TNF therapy.
1-16. (canceled)
A method of treating a subject suffering from rheumatoid arthritis, the method comprising administering to the subject an anti-TNF therapy, wherein the subject has been determined to be responsive to the anti-TNF therapy via a trained machine learning classifier that distinguishes between responsive and non-responsive subjects who have received the anti-TNF therapy, which the trained machine learning classifier predicts non-responsiveness at an accuracy of at least about 90%.
A method of treating a subject suffering from rheumatoid arthritis, the method comprising administering to the subject an alternative to anti-TNF therapy,
A method of treating a subject suffering from rheumatoid arthritis, the method comprising:
Dependencies are inferred from the claim text.