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US 2022/0096352 A1Published application
Human placental collagen compositions and methods of making and using the same
AssigneeCelularity Inc.
InventorsMohit B. BHATIA, Chris LUGO, Qian YE, James W. EDINGER
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Abstract
The present invention provides compositions comprising human placental telopeptide collagen, methods of preparing the compositions, methods of their use and kits comprising the compositions. The compositions, kits and methods are useful, for example, for augmenting or replacing tissue of a mammal.
Claims48
Base-treated, detergent-treated telopeptide collagen.
Detergent-treated telopeptide collagen comprising a detectable amount of fibronectin.
A process for preparing telopeptide collagen from tissue of a mammal that comprises collagen, said process comprising the steps of:
- a. contacting the tissue with an osmotic shock solution to yield a collagen composition;
- b. contacting the collagen composition with a detergent;
- and
- c. contacting the detergent-treated collagen solution with a basic solution.
1 more element
Dependencies are inferred from the claim text.