Loading patent…
AssigneeIndustry-Academic Cooperation Foundation Gyeongsang National University
InventorMyeong Ok KIM
Estimating the term…
The composition for predicting Alzheimer's disease prognosis comprising a detection reagent that specifically binds to any one or more genes selected from the group consisting of (Nitric oxide synthase 1), Aph1B (Anterior pharynx defective 1 homolog B), Ryr3 (Ryanodine receptor 3), Atf6 (Activating transcriptional factor 6), Ip3r (Inositol trisphosphate receptor), Nep (Neprilysin), Cdk5 (cyclin dependent kinase 5) and Abad (Amyloid beta-binding alcohol dehydrogenase), a kit, and a method for providing information on Alzheimer's disease prognosis of the present invention can rapidly and accurately predict the prognosis of Alzheimer's disease, and can determine the prognosis for a drug by comparing the expression level before and after drug administration, so that an appropriate treatment direction can be determined according to the predicted prognosis. Therefore, they have an effect that can greatly contribute to the reduction of mortality due to Alzheimer's disease.
-6. (canceled)
A composition for predicting a clinical stage of Alzheimer's disease comprising a reagent for measuring a level of mRNA of Serca1 (sarco/endoplasmic reticulum Ca2+ ATPase 1) gene or a protein expressed therefrom, wherein the reagent for measuring the level of mRNA of the gene is comprises a primer or probe that specifically binds to the gene and the reagent for measuring the level of the protein includes an antibody or aptamer specific to the protein.
-11. (canceled)
Dependencies are inferred from the claim text.