Compounds for use in system suitability testing of inert lc systems and columns
AssigneeWaters Technologies Corporation
InventorsAmit Patel, Moon Chul Jung, Susan Rzewuski, Matthew A. Lauber, Thomas H. Walter, Kevin Wyndham, Mathew DeLano, Jennifer Simeone
Life of this patent
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Abstract
The present disclosure is directed to a kit for evaluating system inertness. The kit includes a positive control comprising a metal interacting moiety, and a negative control that does not contain a metal interacting moiety. In some embodiments the kit also includes a container to hold a system suitability solution (e.g., an equimolar mixture of the positive control and the negative control).
Claims23
A kit for evaluating system inertness, the kit comprising:
- a first vial comprising a positive control comprising a nucleotide diphosphate with a non-hydrolyzable alpha-beta bond or a chemically modified analog thereof, wherein the positive control contains a metal interacting moiety;
- and
- a second vial comprising a negative control that does not contain a metal interacting moiety.
A kit for evaluating system inertness, the kit comprising:
- a first vial comprising a positive control comprising adenosine-5′-triphosphate (ATP) or a chemically modified analog thereof;
- and
- a second vial comprising a negative control that does not contain a metal interacting moiety.
A kit for evaluating system inertness, the kit comprising:
- a positive control comprising a metal interacting moiety;
- a negative control that does not contain a metal interacting moiety;
- and
- a container to hold a system suitability solution.
Dependencies are inferred from the claim text.