Trace substance optical measuring instrument and measuring method
AssigneeProvigate Inc.
InventorsNorikazu KATAYAMA, Narushi ITO
Life of this patent
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Abstract
Provided is a device for measuring a substance in a solution, provided with: a light source; a micro flow passage including at least a portion of an optical path of light emitted from the light source, and extending along said optical path; and a light receiver for detecting light that has passed through the micro flow passage.
Claims52
An apparatus for measuring a substance in a solution, comprising:
- a light source;
- a micro flow channel including at least a portion of an optical path of light emitted from the light source and extending along the optical path;
- and
- a photodetector for detecting light passed through the micro flow channel.
An apparatus for measuring a substance in a solution, comprising:
- a first light source;
- a second light source;
- a first micro flow channel including at least a portion of a first optical path of light emitted from the first light source and extending along the first optical path;
- a second micro flow channel including at least a portion of a second optical path of light emitted from the second light source and extending along the second optical path;
- a first photodetector for detecting light passed through the first micro flow channel;
- and
- a second photodetector for detecting light passed through the second micro flow channel.
A method for measuring a concentration of albumin, comprising:
- providing the apparatus according to any one of claims 1 to 43;
- providing an original solution including albumin;
- mixing bromocresol purple with the original solution including the albumin, to bind it to the albumin;
- preparing a measurement solution including the albumin to which the bromocresol purple is bound;
- introducing the measurement solution into the micro flow channel of the apparatus;
- performing an optical measurement on the solution in the micro flow channel;
- measuring from the measurement the concentration of the bromocresol purple in the micro flow channel;
- and
- determining from the measured concentration of bromocresol purple the concentration of the albumin in the measurement solution.
The method according to claim 47, wherein the original solution including the albumin is tear fluid or saliva.
The method according to claim 48 or 49, further comprising mixing the original solution and an oxidizing agent, prior to said mixing the bromocresol purple and the original liquid.
Dependencies are inferred from the claim text.