US 2022/0089780 A1 · KLOTHO BETA

Abstract

The invention concerns uses of anti-KLβ agents, and detection of KLβ and/or FGF19 and/or FGFR4.

Claims2

Dependent claims

A method for treating diabetes mellitus, cardiovascular disease, insulin resistance, hypertension, thromboembolic disease or dyslipidemia, comprising administering to an individual in need of such treatment an effective dose of an anti-KLβ antibody.

Dependencies are inferred from the claim text.

Facts

Application

17/411,753Filed 25 Aug 2021

Priority

2 Apr 2007

Published

24 Mar 2022

Term ends

Not estimatedThe source records don’t support an estimate.

Classification45 codes

C07K 16/40
Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies: against enzymes
A61K 31/138
Having aromatic rings , e.g. ketamine, nortriptyline: aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
A61K 31/4196
Having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole: 1,2,4-Triazoles
A61K 31/4745
Ortho- or peri-condensed with heterocyclic ring systems: condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines

Family

Application60/909,699Us provisional application · filed 2 Apr 2007

Application60/916,187Us provisional application · filed 4 May 2007

Application12/594,443Continuation · filed 23 Feb 2010

Application14/302,895Continuation · filed 12 Jun 2014

Application15/701,243Continuation · filed 11 Sep 2017

Application16/829,036Continuation · filed 25 Mar 2020

Application17/094,646Continuation · filed 10 Nov 2020

Application17/411,753Continuation

US 2010/0158914 A1Published application

US 2014/0363435 A1Published application

US 2018/0208677 A1Published application

US 2021/0284753 A1Published application

US 2022/0089780 A1This patent

From the US filing history. Foreign family members aren’t listed.

Facts

Application

17/411,753Filed 25 Aug 2021

Priority

2 Apr 2007

Published

24 Mar 2022

Term ends

Not estimatedThe source records don’t support an estimate.

Classification45 codes

C07K 16/40
Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies: against enzymes
A61K 31/138
Having aromatic rings , e.g. ketamine, nortriptyline: aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
A61K 31/4196
Having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole: 1,2,4-Triazoles
A61K 31/4745
Ortho- or peri-condensed with heterocyclic ring systems: condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines

Family

Application60/909,699Us provisional application · filed 2 Apr 2007

Application60/916,187Us provisional application · filed 4 May 2007

Application12/594,443Continuation · filed 23 Feb 2010

Application14/302,895Continuation · filed 12 Jun 2014

Application15/701,243Continuation · filed 11 Sep 2017

Application16/829,036Continuation · filed 25 Mar 2020

Application17/094,646Continuation · filed 10 Nov 2020

Application17/411,753Continuation

US 2010/0158914 A1Published application

US 2014/0363435 A1Published application

US 2018/0208677 A1Published application

US 2021/0284753 A1Published application

US 2022/0089780 A1This patent

From the US filing history. Foreign family members aren’t listed.

Klotho beta

Life of this patent

Abstract

Claims2

Klotho beta

Life of this patent

Abstract

Claims2