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US 2022/0089758 A1Published application
Novel anti-cd40 antibodies
AssigneeRevmab Biosciences USA, Inc.
InventorsMu-En LIN, Qiu YU, Hui LI, Yaohuang KE
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Abstract
The present disclosure provides anti-CD40 antibodies or antigen-binding fragments thereof, isolated polynucleotides encoding the same, pharmaceutical compositions comprising the same, and the uses thereof.
Claims26
An isolated anti-CD40 antibody or an antigen-binding fragment thereof comprising:
- a) a heavy chain variable region comprising the complementarity determining regions (CDRs) of SEQ ID NOS:
- 13, 15 and 17 in that order;
- and a light chain variable region comprising the CDRs of SEQ ID NO:
- 14, 16 and 18 in that order;
- or
- b) a heavy chain variable region comprising the CDRs of SEQ ID NOS:
- 19, 21 and 23 in that order;
- and a light chain variable region comprising the CDRs of SEQ ID NOS:
- 20, 22 and 24 in that order.
6 more elements
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22-23. (canceled)
27-29. (canceled)
Dependencies are inferred from the claim text.