T-cell receptor modified object
AssigneesKyoto University, Takeda Pharmaceutical Company Limited
InventorsShin KANEKO, Yoshiaki KASSAI, Akira HAYASHI
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Abstract
The present invention provides a variant of a T-cell receptor containing a combination of two polypeptides containing a constant region of a T cell receptor chain selected from the group consisting of α chain, β chain, γ chain and δ chain, wherein the polypeptide does not contain a complementarity determining region (CDR) of the T cell receptor chain, a complementarity determining region (CDR) of the α chain, and a complementarity determining region (CDR) of the β chain.
Claims11
A variant of a T-cell receptor comprising a combination of two polypeptides comprising a constant region of a T cell receptor chain selected from the group consisting of α chain, β chain, γ chain and δ chain, wherein the polypeptide does not comprise a complementarity determining region (CDR) of the T cell receptor chain, a complementarity determining region (CDR) of the α chain, and a complementarity determining region (CDR) of the β chain.
Dependencies are inferred from the claim text.