Cyclic peptide, cell scaffold material, cell separating material, and medium
AssigneeFUJIFILM Corporation
InventorKoichi MINAMI
Life of this patent
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Abstract
There is provided a cyclic peptide containing a cyclic segment containing an RGD sequence and having 8 to 14 amino acid residues. A thioether bond is formed between an amino acid residue Xa located on a most N-terminal side of the cyclic segment and an amino acid residue Xb located on a most C-terminal side of the cyclic segment. However, in a case where one of the amino acid residue Xa and the amino acid residue Xb is a cysteine residue, an α carbon of the other amino acid residue of the amino acid residue Xa and the amino acid residue Xb is separated from a sulfur atom of the cysteine residue by five or more atoms.
Claims19
A cyclic peptide comprising:
- a cyclic segment comprising an RGD sequence and having 8 to 14 amino acid residues, a thioether bond being formed between an amino acid residue Xa located on a most N-terminal side of the cyclic segment and an amino acid residue Xb located on a most C-terminal side of the cyclic segment,
- provided that, in a case where one of the amino acid residue Xa and the amino acid residue Xb is a cysteine residue, an α carbon of the other amino acid residue of the amino acid residue Xa and the amino acid residue Xb is separated from a sulfur atom of the cysteine residue by five or more atoms.
Dependencies are inferred from the claim text.