Carrier Peptide Fragment and Use Thereof

Abstract

The disclosure provides a technology for efficiently introducing a foreign substance into at least cytoplasm of eukaryotic cells from outside the cells. The method disclosed here for introducing a foreign substance of interest in vitro or in vivo into at least cytoplasm of eukaryotic cells from outside the cells includes (1) a step of preparing a foreign substance introduction construct including a carrier fragment composed of KKRTLRKSNRKKR (SEQ ID NO:1) and the foreign substance of interest linked to the N-terminal and/or C-terminal side of the carrier peptide fragment; (2) a step of supplying the foreign substance introduction construct to a sample containing a target eukaryotic cell; and (3) a step of incubating the sample, to which the foreign substance introduction construct has been supplied, to thereby introduce the construct into the eukaryotic cell in the sample.

Dependencies are inferred from the claim text.