Alkynyl nicotinamide compounds as kinase inhibitors

A compound represented by a compound of Formula (I):

• Wherein Y1-Y6==amide;
• O-alkyl such as OMe, OEt, OPr, OBu, OiPr, OCF2, OCF3;
• NH2, NH-alkyl, such as NHMe, NHEt;
• N-(alkyl)2 or N-(heteroalkyl)2, such as NMe2, morpholino, piperazine;
• CN, Cl, Br, iPr, Et, cyclopropyl, butyl, CF3, CHF2, CH2-piperazine analog, CH2-morpholine analog, CH2-piperidine analog, CH2-pyrrolidine analog, CH2-azetidine analog, etc. and X1-X7=CH, CY or N.