Methods for preparing tissue grafts with antimicrobial properties

A method for preparing a tissue graft, comprising:

• providing a tissue graft;
• and
• applying to the tissue graft an antimicrobial solution comprising a zinc compound by contacting the tissue graft with the antimicrobial solution, thereby causing the zinc compound to directly associate with the tissue graft and modify the surface of the allograft tissue,
• wherein the antimicrobial solution exhibits antimicrobial activity of inhibiting or controlling growth of Mycobacterium tuberculosis in the tissue graft and provides deep tissue cleaning.