Back to results
US 2022/0088170 A1Published application
Methods and compositions for inducing protective immunity against filovirus infection
AssigneesBavarian Nordic A/S, Janssen Vaccines & Prevention B.V., The United States of America, as represented by the Secretary, Department of Health and Human Servic
InventorsAriane VOLKMANN, Robin STEIGERWALD, Ulrike DIRMEIER, Maria Grazia PAU, Benoit Christophe Stephan CALLENDRET, Lucy A. WARD
Life of this patent
Estimating the term…
Abstract
The present invention provides compositions, vaccines and methods for inducing protective immunity against filovirus infection, particularly protective immunity against infection of one or more subtypes of Ebola viruses and Marburg virus.
Claims15
A vaccine combination comprising
- (i) a first composition comprising an immunologically effective amount of an adenovirus vector comprising a nucleic acid encoding an antigenic protein of a first filovirus subtype, together with a pharmaceutically acceptable carrier;
- and
- (ii) a second composition comprising an immunologically effective amount of an MVA vector comprising a nucleic acid encoding antigenic proteins of at least two filovirus subtypes, together with a pharmaceutically acceptable carrier;
- wherein the first composition is a priming composition and the second composition is a boosting composition.
1 more element
12-34. (canceled)
Dependencies are inferred from the claim text.