Nail compositions having antifungal properties
AssigneeIsdin, S.A.
InventorsCorinne Jeanne Rose GRANGER, Carlos Ramon TRULLAS CABANAS
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Abstract
It relates to a combination comprising a) rhamnose or a rhamnose-rich polysaccharide; b) a film-forming agent; and c) one or more further active agents selected from: i) a hyaluronic acid derivative selected from the group consisting of hyaluronic acid, a pharmaceutically or cosmetically acceptable salt thereof, and a cationized hyaluronic acid, ii) a silanol compound, and iii) an extract of Pistacia lentiscus; for use in the treatment and/or prevention of fungal infections in human beings. It also relates to this combination per se, and to pharmaceutical or cosmetic topical nail composition containing it.
Claims20
A method for the treatment and/or prevention of fungal infections in human beings, comprising administering an effective amount of the combination comprising:
- a) rhamnose or a rhamnose-rich polysaccharide, wherein the rhamnose-rich polysaccharide comprises rhamnose in an amount equal or higher than 30% w/w;
- b) a film-forming agent;
- and
- c) one or more further active agents selected from:
- i) a hyaluronic acid derivative selected from the group consisting of hyaluronic acid, a pharmaceutically or cosmetically acceptable salt thereof, and a cationized hyaluronic acid, wherein the cationized hyaluronic acid is a hyaluronic acid wherein the hydrogen atom of at least one of the hydroxylic groups or the carboxylic group is replaced by a moiety of formula (III):
- wherein each of R1-R4 independently represents a linear or branched (C1-C6)alkyl group optionally substituted with one or more hydroxyl groups, and X is a halogen ion;
- ii) a silanol compound, and
- iii) an extract of Pistacia lentiscus,
- and one or more pharmaceutically or cosmetically acceptable excipient or carriers, to a subject in need thereof.
A combination comprising:
- a) rhamnose or a rhamnose-rich polysaccharide, wherein the rhamnose-rich polysaccharide comprises rhamnose in an amount equal or higher than 30% w/w;
- b) a film-forming agent;
- and
- c) one or more further active agents selected from:
- i) a hyaluronic acid derivative selected from the group consisting of hyaluronic acid, a pharmaceutically or cosmetically acceptable salt thereof, and a cationized hyaluronic acid, wherein the cationized hyaluronic acid is a hyaluronic acid wherein the hydrogen atom of at least one of the hydroxylic groups or the carboxylic group is replaced by a moiety of formula (III):
- wherein each of R1-R4 independently represents a linear or branched (C1-C6)alkyl group optionally substituted with one or more hydroxyl groups, and X is a halogen ion;
- ii) a silanol compound, and
- iii) an extract of Pistacia lentiscus.
Dependencies are inferred from the claim text.