Method for treating anxiety disorders, headache disorders, and eating disorders with psilocybin

A method of treating post-traumatic stress disorder, the method comprising orally administering a therapeutically effective amount of an oral dosage form, wherein the oral dosage form comprises:

• a crystalline Polymorph A of psilocybin characterized by XRPD peaks at 11.5±0.1, 12.0±0.1, 14.5±0.1, 17.5±0.1 and 19.7±0.1 °2θ, wherein the psilocybin has a chemical purity of greater than 97% as determined by HPLC analysis and
• a pharmaceutically acceptable excipient.

A method of treating post-traumatic stress disorder, the method comprising administering a therapeutically effective amount of psilocybin to a patient in need thereof, wherein the psilocybin comprises a crystalline Polymorph A of psilocybin characterized by X-ray powder diffraction (XRPD) peaks at 11.5±0.1, 12.0±0.1, 14.5±0.1, 17.5±0.1 and 19.7±0.1 °2θ, and

• wherein the psilocybin has a chemical purity of greater than 97% as determined by HPLC analysis.