Maternal dpa for benefit of mother and/or child's mental health
AssigneesAgency for Science, Technology and Research (A*Star), National University of Singapore
InventorsNeerja KARNANI, Gerard Kum Peng WONG, Peter David GLUCKMAN, Michael Joseph MEANEY
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Abstract
Interpretation: This is the first ever report to uncover a tangible lipidomic basis by which maternal emotional well-being may influence fetal neurodevelopment and the later risk for psychopathology. This novel insight points to the potential utility of nutritional approaches among pregnant women with high levels of depressive symptoms in the prevention of offspring risk for later socio-emotional behavioral problems predictive of future psychopathology. Such a novel approach is particularly pertinent in light of the preference to avoid pharmacological interventions such as anti-depressant medications during pregnancy.
Claims11
A method of enhancing the low mood of a peri-partum woman comprising administering an effective amount of docosapentaenoic acid (DPA) to the woman.
A method of enhancing the socio-emotional outcome of a child comprising antenatally administering to the child's mother an effective amount of at least one polyunsaturated fatty acid (PUFA) selected from the group consisting of DPA, eicosapentaenoic acid (EPA), arachidonic acid (AA) and docosahexaenoic acid (DHA).
A maternal nutritional supplement comprising DPA in a tablet or capsule form.
Dependencies are inferred from the claim text.