Compositions, methods, systems and/or kits for preventing and/or treating neoplasms
AssigneeResearch Cancer Institute of America
InventorMohammed Amin Nezami
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Abstract
Provided herein are compositions, methods, systems and/or kits for preventing and/or treating neoplasms using at least one modulator selected from quercetin, sodium phenyl butyrate and epigallocatechin-3-gallate in combination with one or more anti-cancer agents. The compositions, methods, systems and/or kits are used to prevent and/or treat neoplasms that are resistant to the one or more anti-cancer agents when administered alone. Also provided are nanoformulations based on nanoparticles comprising one or more anti-cancer agents and/or one or more modulators for preventing and/or treating neoplasms.
Claims51
A pharmaceutical composition for prophylaxis, treatment or both of a neoplasm, comprising:
- at least one anti-cancer agent
- wherein the at least one anti-cancer agent is Temodar;
- and
- a first an anti-cancer response modulator,
- wherein the anti-cancer response modulator is a first anti-cancer response modulator selected form the group consisting of quercetin, sodium phenyl butyrate (SPB) and epigallocatechin-3-gallate (EGCG).
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Dependencies are inferred from the claim text.