Formulations for oral delivery of adsorbents in the gut
AssigneeDa Volterra
InventorsFrancois LESCURE, Jean DE GUNZBURG
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Abstract
The invention relates to a formulation for the delayed and controlled delivery of an adsorbent into the lower intestine of mammals. The formulation includes a carrageenan and an adsorbent, such as activated charcoal. The invention further relates to uses of this formulation, in particular to pharmaceutical uses. In one embodiment, the formulation is used to eliminate or reduce the side effects in the intestine, in particular in the colon, of pharmaceutical agents that are administered as a treatment for a disorder, but that have side effects when they reach the late ileum, the caecum or the colon.
Claims32
1-22. (canceled)
A composition comprising an adsorbent mixed with carrageenan.
The formulation of claim 13, wherein the pH-independent insoluble polymers are selected from the group consisting of ethylcellulose polymers and ethyl acrylate methyl methacrylate copolymers.
Dependencies are inferred from the claim text.