Vascular grafts and method for preserving patency of the same
AssigneeHealionics Corporation
InventorsAndrew J. Marshall, Max Maginness, Adrienne Oda, Brandt Scanlan
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Abstract
This disclosure provides prosthetic arteriovenous grafts having a blood-contacting layer; an intermediate layer; and a tissue-interface layer formed of a microporous biomaterial with a textured microporous surface, the prosthetic arteriovenous grafts providing vascular access for hemodialysis and being capable of reducing perigraft fibrotic capsular formation, and a method of maintaining the patency of the prosthetic arteriovenous grafts.
Claims22
A method for reducing or preventing stenosis within or near either end of an implanted vascular graft, the method comprising:
- connecting a vascular graft to one or more native blood vessels to provide the implanted vascular graft in tissue, wherein the vascular graft has a tissue-interface layer having textured microporous surface that reduces constriction from the tissue response to the implanted vascular graft to a degree that influences development of stenosis.
A method for reducing or preventing development of neointimal hyperplasia within or near either end of an implanted vascular graft, the method comprising:
- connecting a vascular graft to one or more native blood vessels to provide the implanted vascular graft in tissue, wherein the vascular graft has a tissue-interface layer having textured microporous surface that reduces constriction from the tissue response to the implanted vascular graft to a degree that reduces or prevents development of neointimal hyperplasia.
Dependencies are inferred from the claim text.