Mechanism and device for left atrial appendage occlusion with electrical isolation
OwnerRobert Fishelinventor
Life of this patent
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Abstract
Left atrial appendage (LAA) occlusion device including a membrane, a plurality of fixation splines and a deployment hub, the plurality of fixation splines for affixing the LAA occlusion device to an ostium of the LAA, the deployment hub being positioned in the membrane, the deployment hub including a threaded aperture and a one-way valve, for enabling a toxin to be entered into the LAA through the deployment hub.
Claims32
Left atrial appendage (LAA) occlusion device comprising:
- a semi-permeable membrane having semi-permeability in only one direction, for covering an ostium of said LAA;
- and
- a deployment hub, positioned in said membrane,
- wherein said deployment hub comprises a one-way valve, for enabling a toxin to be entered into said LAA through said deployment hub;
- and
- wherein said semi-permeable membrane enables said toxin to seep out of said LAA and prevents blood from entering said LAA.
(canceled)
The LAA occlusion device according to claim 23, wherein said threaded aperture enables at least one of a catheter and a delivery device to be coupled with said LAA occlusion device for placement in said LAA.
The LAA occlusion device according to claim 23, wherein said plurality of fixation splines is made from a biocompatible metal.
The LAA occlusion device according to claim 23, wherein said plurality of fixation splines has an open shape and a closed shape.
The LAA occlusion device according to claim 23, wherein said plurality of fixation splines is arranged radially around said deployment hub.
The LAA occlusion device according to claim 23, wherein said plurality of fixation splines is formed as a spring and is held under pressure by a delivery sheath.
Left atrial appendage (LAA) occlusion device comprising:
- a membrane;
- a plurality of fixation splines, for affixing said LAA occlusion device to an ostium of said LAA;
- and
- a deployment hub, positioned in said membrane,
- said deployment hub comprising:
- a threaded aperture;
- a lumen, housing a toxin;
- a semi-permeable membrane covering a proximal end of said lumen of said deployment hub;
- and
- a timed drug release mechanism.
Fluid activated timed drug release mechanism comprising:
- a deployment hub, for housing a target drug and a fluid activated glue-dissolving enzyme;
- a molecular sieve, positioned over a proximal side of said deployment hub, for enabling a fluid to enter said deployment hub;
- and
- a glue, positioned over a distal side of said deployment hub,
- wherein said molecular sieve enables said fluid to enter said deployment hub for activating said fluid activated glue-dissolving enzyme;
- and
- wherein said fluid activated glue-dissolving enzyme dissolves said glue, thereby enabling said target drug to be released via said distal side.
Method for deploying a left atrial appendage (LAA) occlusion system in a patient, said LAA occlusion system comprising a membrane and a deployment hub, positioned in said membrane, comprising the procedures of:
- inserting a guidewire into said patient for accessing a right atrium of a heart of said patient;
- puncturing a transseptal point in said heart for enabling access to said LAA;
- moving an injection tube loaded with said LAA occlusion system over said guidewire such that said LAA occlusion system is within said LAA;
- deploying said LAA occlusion system such that said membrane is held to tissue forming an ostium of said LAA;
- injecting a toxin via said injection tube into said LAA through a one-way valve of said deployment hub;
- inserting an isolation device and a delivery sheath over said injection tube;
- positioning said isolation device and said delivery sheath to tissue surrounding said ostium of said LAA;
- pulling back said delivery sheath such that an expandable section of said isolation device expands around said tissue surrounding said ostium;
- temporarily coupling said isolation device with an area around a vestibule of said LAA thereby forming a lumen around said LAA;
- releasing said injection tube from said LAA occlusion system while maintaining said injection tube proximate to said lumen around said LAA;
- releasing said toxin into said lumen around said LAA via said injection tube;
- removing said injection tube from said guidewire and inserting a suction tube over said guidewire;
- removing said toxin in said lumen around said LAA with said suction tube;
- and
- removing said delivery sheath, said isolation device and said guidewire.
Method for deploying a left atrial appendage (LAA) occlusion system in a patient, said LAA occlusion system comprising a semi-permeable membrane having semi-permeability in only one direction and a deployment hub, positioned in said semi-permeable membrane, comprising the procedures of:
- inserting a guidewire into said patient for accessing a right atrium of a heart of said patient;
- puncturing a transseptal point in said heart for enabling access to said LAA;
- moving an injection tube loaded with said LAA occlusion system over said guidewire such that said LAA occlusion system is within said LAA;
- deploying said LAA occlusion system such that said semi-permeable membrane is held to tissue forming an ostium of said LAA;
- injecting a toxin via said injection tube into said LAA through a one-way valve of said deployment hub;
- removing said injection tube and said guidewire from said patient;
- and
- removing said toxin from said LAA via said semi-permeable membrane.
Dependencies are inferred from the claim text.