Screening methods using gprc6a taste receptors and pet food products and compositions prepared using the same
AssigneeMars, Incorporated
InventorsScott Joseph McGrane, Matthew Ronald Gibbs, Boris Klebansky, Richard Masten Fine
Life of this patent
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Abstract
The presently disclosed subject matter relates to methods of screening raw materials and pet food products to manufacture a palatable pet food product. The presently disclosed subject matter also relates to methods for identifying compounds that modulate the activity and/or expression of a taste receptor.
Claims17
A method for identifying a compound that modulates the activity of a GPRC6A receptor comprising
- (a) contacting a test agent with a polypeptide comprising a GPRC6A receptor or a functional fragment thereof,
- (b) measuring a biological activity of the polypeptide, and
- (c) selecting as the compound, a test agent that increases or decreases the activity of the polypeptide.
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A method for increasing palatability of a pet foodstuff comprising:
- admixing a compound or a composition comprising the compound with a pet foodstuff, wherein the compound, when brought to contact with a polypeptide comprising a GPRC6A receptor or a functional fragment thereof, is capable of increasing a biological activity of the polypeptide.
A composition comprising a compound, wherein the compound, when brought to contact with a polypeptide comprising a GPRC6A receptor or a functional fragment thereof, is capable of increasing or decrease a biological activity of a polypeptide comprising a GPRC6A receptor or a functional fragment thereof.
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Dependencies are inferred from the claim text.