Microfluidic devices
AssigneeHewlett-Packard Development Company, L.P.
InventorsViktor SHKOLNIKOV, Alexander GOVYADINOV
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Abstract
The present disclosure relates to a microfluidic device including a microfluidic substrate and dry reagent-containing polymer particles. The microfluidic substrate includes a microfluidic-retaining region within the microfluidic substrate that is fluidly coupled to multiple microfluidic channels. The dry reagent-containing polymer particles include reagent and a degradable polymer. The reagent is releasable from the degradable polymer when exposed to release fluid. The dry reagent-containing particles are retained within the microfluidic substrate at the microfluidic-retaining region in position to release reagent into the egress microfluidic channel upon flow of release fluid from the ingress microfluidic channel through the microfluidic-retaining region.
Claims15
A microfluidic device, comprising:
- a microfluidic substrate, including a microfluidic-retaining region within the microfluidic substrate that is fluidly coupled to multiple microfluidic channels;
- and
- dry reagent-containing polymer particles including reagent and a degradable polymer, wherein the reagent is releasable from the degradable polymer when exposed to release fluid, wherein the dry reagent-containing polymer particles are retained within the microfluidic substrate at the microfluidic-retaining region in position to release reagent into the egress microfluidic channel upon flow of release fluid from the ingress microfluidic channel through the microfluidic-retaining region.
A microfluidic system, comprising:
- a microfluidic device, including:
- a microfluidic substrate, including a microfluidic-retaining region with an open channel positioned within the microfluidic substrate, and
- a lid positionable over the microfluidic substrate to form an enclosed microfluidic-retaining region;
- and
- a reagent loadable in the microfluidic-retaining region to be enclosed by the lid,
- wherein the enclosed microfluidic-retaining region is fluidly coupled to multiple microfluidic channels.
A method of manufacturing a microfluidic device, comprising loading dry reagent-containing polymer particles into a microfluidic-retaining region of a microfluidic substrate that is fluidly coupled to multiple microfluidic channels, wherein the dry reagent-containing polymer particles include a reagent and a degradable polymer, wherein the dry reagent-containing polymer particles are retained within the microfluidic substrate at the microfluidic-retaining region in position to release reagent into an egress microfluidic channel while exposed to a release fluid passed through the microfluidic-retaining region.
Dependencies are inferred from the claim text.