Diagnostic
AssigneeHAV Vaccines Limited
InventorJohn HERMON-TAYLOR
Life of this patent
Estimating the term…
Abstract
A method of diagnosing or monitoring Mycobacterium avium subspecies paratuberculosis (MAP) infection, which method comprises detecting the presence of the polypeptide (MAP P900) encoded by the positive strand of IS900, or a fragment thereof, in a sample from a subject, wherein MAP P900, or a fragment thereof, is detected using an antibody, or an antigen-binding fragment thereof, that binds to MAP P900.
Claims22
A method of detecting Mycobacterium avium subspecies paratuberculosis (MAP) in a human or animal subject, in a food product or in an environmental sample, which method comprises:
- (a) obtaining a body fluid or tissue sample from the human or animal subject, or a sample of the food product, or the environmental sample;
- (b) contacting the sample with an antibody, or an antigen-binding fragment thereof, that binds an extracellular portion of the polypeptide (MAP P900) encoded by the positive strand of IS900, or a fragment thereof, in the sample;
- and
- (c) detecting binding of the antibody, or the antigen-binding fragment thereof, to MAP P900 in the sample, wherein detection of the binding of the antibody, or the antigen-binding fragment thereof to MAP P900 indicates the presence of MAP.
-24. (canceled)
The method of wherein the food product is milk or other dairy product or a meat product.
(canceled)
-36. (canceled)
Dependencies are inferred from the claim text.