Method of identification of methicillin-resistant staphylococcus aureus
AssigneeChina Medical University Hospital
InventorsDer-Yang Cho, Jiaxin Yu, Ni Tien, Chao-Jung Chen
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Abstract
Disclosed is a method for identifying methicillin-resistant Staphylococcus aureus through detection a mass signal at m/z of 6580-6600 in the MALDI-TOF mass spectrum. Also disclosed is a novel peptide biomarker, which consists of SEQ NO ID:5 and the use thereof for detection and/or identification of methicillin-resistant Staphylococcus aureus.
Claims14
A method for identifying methicillin-resistant Staphylococcus aureus, comprising:
- (a) providing a bacterial sample;
- (b) depositing the bacterial sample on a matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF) mass spectrometer target plate;
- (c) acquiring a MALDI-TOF mass spectrum of the bacterial sample;
- and
- (d) determining the presence of a mass signal at m/z of 6580-6600 in the MALDI-TOF mass spectrum, and identifying the bacterial sample which comprises methicillin-resistant Staphylococcus aureus.
A peptide for identifying methicillin-resistant Staphylococcus aureus consists of SEQ NO ID:5.
A method for identifying methicillin-resistant Staphylococcus aureus, comprising:
- (a) providing a bacterial sample;
- and
- (b) determining the presence of a peptide which consists of SEQ NO ID:5, and identifying the bacterial sample which comprises methicillin-resistant Staphylococcus aureus.
Dependencies are inferred from the claim text.