Preparation of 6-aminocaproic acid from 5-formyl valeric acid
AssigneeGenomatica, Inc.
InventorsPetronella Catharina Raemakers-Franken, Martin Schurmann, Axel Christoph Trefzer, Stefaan Marie Andre De Wildeman
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Abstract
The invention relates to a method for preparing 6-aminocaproic acid (hereinafter also referred to as ‘6-ACA’) using a biocatalyst. The invention further relates to a method for preparing ε-caprolactam (hereafter referred to as ‘caprolactam’) by cyclising such 6-ACA. The invention further relates to a host cell, a micro-organism, or a polynucleotide which may be used in the preparation of 6-ACA or caprolactam.
Claims14
(canceled)
Method for preparing 6-aminocaproic acid, wherein the 6-aminocaproic acid is prepared from 5-formylpentanoate, using a recombinant host cell comprising at least one biocatalyst, wherein the biocatalyst is an enzyme capable of catalysing a transamination and/or a reductive amination selected from the group of aminotransferases (E.C. 2.6.1) and amino acid dehydrogenases (E.C.1.4.1).
3-4. (canceled)
8-15. (canceled)
A recombinant host cell comprising a nucleic acid sequence encoding an enzyme with 5-formylpentanoate aminotransferase activity.
19-22. (canceled)
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Dependencies are inferred from the claim text.